Active ingredientTreprostinilCat. No. P-T186-001CAS 81846-19-7
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Impurity or related compound · Treprostinil family
Pharmaceutical analytical standardTreprostinil Methyl Ester
Synonyms: Treprestinil methyl ester, Acetic acid, 2-(((1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-((3S)-3-hydroxyoctyl)-1H-benz(f)inden-5-yl)oxy)-, methyl ester, Treprostinil Diethanolamine (RS)
- Cat. No.
- P-T186-027
- CAS
- 81845-98-9
- Alternative CAS
- N/A
- Formula
- C24H36O5
- Molecular weight
- 404.55 g/mol
- Category
- Impurity or related compound
Family: Treprostinil
A stable prostacyclin analogue that widens the lung's blood vessels and curbs platelet aggregation: approved in the United States in 2002, it is used in pulmonary arterial hypertension by subcutaneous, intravenous, inhaled or oral route.
Did you know?Epoprostenol, the prostacyclin used as a medicine, stays active in the blood for only a few minutes; treprostinil, stable at room temperature, lasts a few hours and can be infused under the skin with a small pump.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Treprostinil family
Active ingredientTreprostinilCat. No. P-T186-001CAS 81846-19-7
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Impurity(3aR) Treprostinil ImpurityCat. No. P-T186-006
Impurity15-epi-TreprostinilCat. No. P-T186-007CAS 343247-13-2
ImpurityDescarboxymethyl Cyanomethyl TreprostinilCat. No. P-T186-008CAS 101692-03-9
ImpurityDescarboxymethyl treprostinilCat. No. P-T186-009CAS 101692-02-8
ImpurityTreprostinil Chloro Impurity (Mixture of Diastereomers)Cat. No. P-T186-010
Active ingredientTreprostinil DiolamineCat. No. P-T186-013CAS 830354-48-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.