Pharmacopoeial impurityTriclabendazole EP Impurity ACat. No. P-T197-002CAS 100648-13-3
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Active ingredient · Triclabendazole family
Pharmaceutical analytical standardTriclabendazole
Synonyms: 6-chloro-5-(2,3-dichlorophenoxy)-2-methylsulfanyl-1H-benzimidazole, Fasinex, Egaten, Egaten tm
- Cat. No.
- P-T197-001
- CAS
- 68786-66-3
- Alternative CAS
- N/A
- Formula
- C14H9Cl3N2OS
- Molecular weight
- 359.65 g/mol
- Category
- Active ingredient (API)
A benzimidazole anthelmintic, long used in veterinary medicine too, that treats fascioliasis and paragonimiasis in humans, infections by flatworms of the liver and lungs; in the United States it was approved for human use in 2019.
Did you know?It is an unusual benzimidazole: it has a chlorinated benzene ring and, unlike its relatives, no carbamate group; it is on the WHO List of Essential Medicines.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Triclabendazole CRSEP Y0001737
- Triclabendazole for system suitability CRSEP Y0001723
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ImpurityKetotriclabendazoleCat. No. P-T197-007CAS 1201920-88-8
ImpurityAmino Triclabendazole HClCat. No. P-T197-008
ImpurityHydroxy TriclabendazoleCat. No. P-T197-009CAS 109536-21-2
ImpurityN1-MethyltriclabendazoleCat. No. P-T197-010CAS 145770-88-3Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.