Active ingredientTrifaroteneCat. No. P-T201-001CAS 895542-09-3
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Impurity or related compound · Trifarotene family
Pharmaceutical analytical standardTrifarotene Impurity 8
Synonyms: 4-[3-(3-tert-Butyl-4-pyrrolidin-1-ylphenyl)-4-(2-oxoethoxy)phenyl]benzoic acid
- Cat. No.
- P-T201-014
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C29H31NO4
- Molecular weight
- 457.57 g/mol
- Category
- Impurity or related compound
Family: Trifarotene
A fourth-generation topical retinoid that selectively activates the retinoic acid receptor RAR-gamma, approved in the United States in October 2019 for the treatment of acne vulgaris.
Did you know?Although it was born as an acne treatment, it has received orphan drug designation for congenital ichthyosis, a rare skin disease, in both the United States and Europe.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Trifarotene family
Active ingredientTrifaroteneCat. No. P-T201-001CAS 895542-09-3
ImpurityTrifarotene Impurity 1Cat. No. P-T201-002CAS 850012-53-2
ImpurityTrifarotene Impurity 2Cat. No. P-T201-003CAS 895543-00-7
ImpurityTrifarotene Impurity 3Cat. No. P-T201-004CAS 895542-84-4
ImpurityTrifarotene Impurity 4Cat. No. P-T201-005CAS 895542-96-8
ImpurityTrifarotene Biphenyl Acid ImpurityCat. No. P-T201-006CAS 895543-28-9
ImpurityTrifarotene DecanoateCat. No. P-T201-008
ImpurityTrifarotene Des Bromo Acid ImpurityCat. No. P-T201-009CAS 46994-29-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.