Active ingredientTrimetazidineCat. No. P-T214-001CAS 5011-34-7
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Pharmacopoeial impurity · Trimetazidine family
Pharmaceutical analytical standardTrimetazidine EP Impurity H
Synonyms: Ethyl 4-((2,3,4-trimethoxyphenyl)methyl)piperazine-1-carboxylate, ethyl 4-[(2,3,4-trimethoxyphenyl)methyl]piperazine-1-carboxylate, Trimetazidine N-Carboxylic Acid Ethyl Ester, Trimetazidine Impurity H
- Cat. No.
- P-T214-012
- CAS
- 53531-01-4
- Alternative CAS
- N/A
- Formula
- C17H26N2O5
- Molecular weight
- 338.40 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Trimetazidine
A metabolic anti-anginal medicine developed in France in the 1970s: it protects heart cells when they receive little oxygen and is used in angina pectoris, added to other medicines.
Did you know?It nudges the heart to burn more glucose and fewer fatty acids: glucose delivers the same energy while using less oxygen, a valuable advantage when blood flow is poor.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Trimetazidine family
Active ingredientTrimetazidineCat. No. P-T214-001CAS 5011-34-7
Active ingredientTrimetazidine DihydrochlorideCat. No. P-T214-002CAS 13171-25-0
Pharmacopoeial impurityTrimetazidine EP Impurity A DihydrochlorideCat. No. P-T214-003CAS 107049-57-0
Pharmacopoeial impurityTrimetazidine EP Impurity ACat. No. P-T214-004CAS 52146-35-7
Pharmacopoeial impurityTrimetazidine EP Impurity BCat. No. P-T214-005CAS 1257-19-8
Pharmacopoeial impurityTrimetazidine EP Impurity CCat. No. P-T214-006CAS 2103-57-3
Pharmacopoeial impurityTrimetazidine EP Impurity DCat. No. P-T214-007CAS 71989-96-3
Pharmacopoeial impurityTrimetazidine EP Impurity E DihydrochlorideCat. No. P-T214-008CAS 2518359-32-3Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.