Active ingredientTrimethobenzamide HClCat. No. P-T216-002CAS 554-92-7
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Active ingredient · Trimethobenzamide family
Pharmaceutical analytical standardTrimethobenzamide
Synonyms: Trimetobenzamida, Ametik damla, Benzamide, N-(p-(2-(dimethylamino)ethoxy)benzyl)-3,4,5-trimethoxy-, Benzamide, N-((4-(2-(dimethylamino)ethoxy)phenyl)methyl)-3,4,5-trimethoxy-, Trimetobenzamide, N-((4-(2-(dimethylamino)ethoxy)phenyl)methyl)-3,4,5-trimethoxybenzamide, N-(4-(2-(Dimethylamino)ethoxy)benzyl)-3,4,5-trimethoxybenzamide, Emedur, Tebamide, Tribenzagan, Benzacot, Stemetic, N-((2-Dimethylaminoethoxy)benzyl)-3,4,5-trimethoxybenzamide
- Cat. No.
- P-T216-001
- CAS
- 138-56-7
- Alternative CAS
- 554-92-7 (hydrochloride)
- Formula
- C21H28N2O5
- Molecular weight
- 388.46 g/mol
- Category
- Active ingredient (API)
An antiemetic of the benzamide family: it blocks dopamine D2 receptors and is believed to act on the chemoreceptor trigger zone of the medulla, the brain area that triggers vomiting. It is used to prevent nausea and vomiting.
Did you know?Its name describes its structure: 'trimetho' refers to the three methoxy groups attached at positions 3, 4 and 5 of the benzene ring of the benzamide.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Trimethobenzamide family
Active ingredientTrimethobenzamide HClCat. No. P-T216-002CAS 554-92-7
Isotopically labelledTrimethobenzamide-d4Cat. No. P-T216-003
Isotopically labelledTrimethobenzamide-d6Cat. No. P-T216-004
NitrosamineN-Nitroso TrimethobenzamideCat. No. P-T216-005
NitrosamineN-Nitroso-N-Desmethyl TrimethobenzamideCat. No. P-T216-006
ImpurityN-Desmethyl Trimethobenzamide HClCat. No. P-T216-007
ImpurityTrimethobenzamide N-OxideCat. No. P-T216-008CAS 2415449-18-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.