Pharmacopoeial impurity(1R,3R)-Tryptophan EP Impurity ICat. No. P-T232-002CAS 96149-76-7
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Pharmacopoeial impurity · Tryptophan family
Pharmaceutical analytical standardTryptophan EP Impurity A
Synonyms: 1,1'-Ethylidenebis(L-tryptophan), L-Tryptophan, 1,1'-ethylidenebis-, Peak E, Tryptophan USP Related Compound A
- Cat. No.
- P-T232-009
- CAS
- 132685-02-0
- Alternative CAS
- N/A
- Formula
- C24H26N4O4
- Molecular weight
- 434.50 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Tryptophan
An essential amino acid, which the body cannot make and must obtain from food: besides building proteins it is the precursor of serotonin, from which melatonin derives, and of niacin (vitamin B3). It was isolated in 1901 by Frederick Gowland Hopkins and Sydney Cole from milk casein.
Did you know?Its name was coined in the late 19th century, before the molecule had even been isolated: it joins trypsin and the Greek phainein, 'to appear', because it appeared when proteins were digested by trypsin.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- 1,1-Ethylidenebistryptophan CRSEP E2205500
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Pharmacopoeial impurityTryptophan EP Impurity A DiHClCat. No. P-T232-010Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
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