Isotopically labelledVadadustat-d5Cat. No. P-V002-002CAS 2229917-78-4
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Active ingredient · Vadadustat family
Pharmaceutical analytical standardVadadustat
Synonyms: AKB-6548, 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid, Vafseo, N-(5-(3-Chlorophenyl)-3-hydroxypyridine-2-carbonyl)glycine, Glycine, N-((5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl)carbonyl)-, N-((5-(3-Chlorophenyl)-3-hydroxy-2-pyridinyl)carbonyl)glycine
- Cat. No.
- P-V002-001
- CAS
- 1000025-07-9
- Alternative CAS
- N/A
- Formula
- C14H11ClN2O4
- Molecular weight
- 306.70 g/mol
- Category
- Active ingredient (API)
An oral inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase, used for anaemia of chronic kidney disease in patients on dialysis; it was approved in the European Union in 2023 and in the United States in 2024.
Did you know?It tricks the body by mimicking its natural response to a lack of oxygen, as happens at high altitude: the body then makes more of its own erythropoietin and uses iron better.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Vadadustat family
Isotopically labelledVadadustat-d5Cat. No. P-V002-002CAS 2229917-78-4Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.