Active ingredientValdecoxibCat. No. P-V005-001CAS 181695-72-7
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Impurity or related compound · Valdecoxib family
Pharmaceutical analytical standardValdecoxib Impurity 28
Synonyms: 3-(5-Methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonic acid, 3-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonic acid
- Cat. No.
- P-V005-042
- CAS
- 1773487-90-3
- Alternative CAS
- N/A
- Formula
- C16H13NO4S
- Molecular weight
- 315.34 g/mol
- Category
- Impurity or related compound
Family: Valdecoxib
A selective COX-2 inhibitor among the non-steroidal anti-inflammatory drugs, approved in the United States in 2001 for osteoarthritis, rheumatoid arthritis and menstrual pain; it was withdrawn from the market in 2005.
Did you know?It lives on through parecoxib, a water-soluble injectable prodrug approved in Europe in 2002 for post-operative pain, which the body converts into valdecoxib itself.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Valdecoxib family
Active ingredientValdecoxibCat. No. P-V005-001CAS 181695-72-7
Isotopically labelledValdecoxib-d3Cat. No. P-V005-002CAS 1219794-90-7
Impurity1-Hydroxy ValdecoxibCat. No. P-V005-003CAS 181695-81-8
ImpurityValdecoxib Impurity 1Cat. No. P-V005-004CAS 1037546-03-4
ImpurityValdecoxib Impurity 2Cat. No. P-V005-005CAS 2304623-42-3
ImpurityValdecoxib Impurity 3Cat. No. P-V005-006CAS 850829-59-3
Impurity3-(5-Methyl-3-phenylisoxazol-4-yl)benzenesulfonyl chlorideCat. No. P-V005-007CAS 1709956-95-5
ImpurityValdecoxib Impurity 4Cat. No. P-V005-008CAS 386273-25-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.