Isotopically labelledVernakalant-d6 HClCat. No. P-V032-002CAS 866455-16-5
Drag to rotate
Active ingredient · Vernakalant family
Pharmaceutical analytical standardVernakalant HCl
Synonyms: Vernakalant Hydrochloride, Brinavess, Kynapid
- Cat. No.
- P-V032-001
- CAS
- 748810-28-8
- Alternative CAS
- 794466-70-9 (free base)
- 605683-48-5 (alternative CAS, same compound)
- Formula
- C20H31NO4·HCl
- Molecular weight
- 385.93 g/mol
- Category
- Active ingredient (API)
An antiarrhythmic that acts mainly on potassium and sodium channels in the atria: given by intravenous infusion, it rapidly restores normal rhythm in recent-onset atrial fibrillation. Approved in the European Union in September 2010.
Did you know?Its molecule has three asymmetric carbon atoms, so eight possible stereoisomers: the medicine contains only one of them, the RRR form.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Vernakalant family
Isotopically labelledVernakalant-d6 HClCat. No. P-V032-002CAS 866455-16-5
ImpurityVernakalant Impurity 1 ((3S,1S,2S)-Isomer) HydrochlorideCat. No. P-V032-003CAS 795282-00-7
ImpurityVernakalant Impurity 2 ((3R,1S,2R)-Isomer)Cat. No. P-V032-004CAS 795282-27-8
ImpurityVernakalant Impurity HCl (3R,1S,2S)Cat. No. P-V032-008CAS 795281-93-5
ImpurityVernakalant Impurity HCl (3S,1R,2R)Cat. No. P-V032-009CAS 795281-99-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.