Active ingredientNaftifine HClCat. No. P-N010-001CAS 65473-14-5
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Impurity or related compound · Naftifine family
Pharmaceutical analytical standard(Z)-Naftifine HCl
Synonyms: (Z)-Naftifine Hydrochloride, Cis-Naftifine, Naftifine, (Z)-
- Cat. No.
- P-N010-005
- CAS
- 79416-70-9
- Alternative CAS
- 65473-08-7 (free base)
- Formula
- C21H21N·HCl
- Molecular weight
- 323.86 g/mol
- Category
- Impurity or related compound
Family: Naftifine
A topical antifungal developed in Vienna, Austria: it was the first successful drug of the allylamine class and is used in creams and gels against fungal skin infections.
Did you know?It blocks the enzyme squalene epoxidase: the fungus is left without ergosterol, essential for its membrane, and accumulates squalene, which is lethal for some species.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Naftifine family
Active ingredientNaftifine HClCat. No. P-N010-001CAS 65473-14-5
Isotopically labelledNaftifine-d3 HClCat. No. P-N010-002
Isotopically labelledNaftifine-d5Cat. No. P-N010-003
Impurity1-ChloromethylnaphthaleneCat. No. P-N010-006CAS 86-52-2
ImpurityNaftifine Impurity 1Cat. No. P-N010-007CAS 98977-93-6
ImpurityNaftifine Impurity 2Cat. No. P-N010-008CAS 98977-94-7
ImpurityDesmethyl Naftifine HClCat. No. P-N010-009CAS 98978-52-0
ImpurityNaftifine Impurity 3Cat. No. P-N010-010CAS 16413-71-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.