Active ingredient · Zalcitabine family
Pharmaceutical analytical standardZalcitabine
Synonyms: Dideoxycytidine, 4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one, ddCyd, Cytidine, 2',3'-dideoxy-, NSC 606170, ddC (Antiviral), HIVID, Zalcitibine, Hivid(TM), ddC & GM-CSF, ddC & sCD4, PC-SOD & ddC, DDC (DDC), ddC & IFNalpha, beta-D-DDC, Dideoxycytidine (DDC), ddC & Interferonalpha, Pharmakon1600-01502360, beta-D-2',3'-Dideoxycytidine, Lecithinized superoxide dismutase & beta-D-2',3'-Dideoxycytidine, NSC 759655, beta-D-2',3'-Dideoxycytidine & Granulocyte-macrophage colony-stimulating factor
- Cat. No.
- P-Z002-001
- CAS
- 7481-89-2
- Alternative CAS
- N/A
- Formula
- C9H13N3O3
- Molecular weight
- 211.22 g/mol
- Category
- Active ingredient (API)
A nucleoside analogue antiretroviral derived from cytidine (ddC), developed against HIV at the US National Cancer Institute: in 1992 it became the third antiretroviral approved by the FDA, and it was withdrawn from the market at the end of 2006.
Did you know?Chemist Jerome Horwitz first synthesised it in the 1960s; in 1964 he had also made zidovudine (AZT), then intended as an anticancer drug.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
Shipped under controlled temperature when the molecule requires it.
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Sent with every order.
Follow your shipment live, from our warehouse to your lab.
Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.