Active ingredientZanamivirCat. No. P-Z005-001CAS 139110-80-8
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Pharmacopoeial impurity · Zanamivir family
Pharmaceutical analytical standardZanamivir EP Impurity E
Synonyms: Carbamimidoyl zanamivir, Zanamivir EP Impurity E ( Free Base)
- Cat. No.
- P-Z005-004
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C13H22N6O7
- Molecular weight
- 374.35 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Zanamivir
A neuraminidase inhibitor antiviral active against influenza A and B, created in 1989 in Australia by a team led by Peter Colman and Joseph Varghese and approved in 1999 in the United States and Europe; it is taken by inhalation.
Did you know?It was designed starting from the X-ray structure of neuraminidase, the enzyme the virus uses to break free from infected cells, and it was the first inhibitor of this class to be developed commercially.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Zanamivir family
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Pharmacopoeial impurityZanamivir EP Impurity DCat. No. P-Z005-003CAS 179531-53-4
Pharmacopoeial impurityZanamivir EP Impurity HCat. No. P-Z005-005CAS 179531-57-8
Impurity1H-Pyrazole-1-Carboxamidine HClCat. No. P-Z005-007CAS 4023-02-3
ImpurityZanamivir Azide Methyl EsterCat. No. P-Z005-008CAS 152178-79-5
ImpurityZanamivir Azide Triacetate Methyl EsterCat. No. P-Z005-009CAS 130525-58-5
ImpurityZanamivir DimerCat. No. P-Z005-010Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.