ImpurityZasocitinib Impurity 1Cat. No. P-Z008-002CAS 2469042-39-3
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Active ingredient · Zasocitinib family
Pharmaceutical analytical standardZasocitinib
Synonyms: TAK-279, N-((1R,2R)-2-methoxycyclobutyl)-7-(methylamino)-5-((2-oxo(1(2H),2'-bipyridin)-3-yl)amino)-pyrazolo(1,5-a)pyrimidine-3-carboxamide, N-((1R,2R)-2-methoxycyclobutyl)-7-(methylamino)-5-((2-oxo-2H-(1,2'-bipyridin)-3-yl)amino)pyrazolo(1,5-a)pyrimidine-3-carboxamide, Pyrazolo(1,5-a)pyrimidine-3-carboxamide, N-((1R,2R)-2-methoxycyclobutyl)-7-(methylamino)-5-((2-oxo(1(2H),2'-bipyridin)-3-yl)amino)-
- Cat. No.
- P-Z008-001
- CAS
- 2272904-53-5
- Alternative CAS
- N/A
- Formula
- C23H24N8O3
- Molecular weight
- 460.50 g/mol
- Category
- Active ingredient (API)
An oral, allosteric inhibitor of the enzyme TYK2, involved in signalling by cytokines such as IL-23; it has been studied in psoriasis, psoriatic arthritis and Crohn's disease, with positive phase 3 results in plaque psoriasis announced in late 2025.
Did you know?In laboratory tests it proved more than a million times more selective for TYK2 than for its cousins JAK1, JAK2 and JAK3, enzymes of the same family.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Zasocitinib family
ImpurityZasocitinib Impurity 1Cat. No. P-Z008-002CAS 2469042-39-3
ImpurityZasocitinib Impurity 2Cat. No. P-Z008-003CAS 2271470-66-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.