Pharmacopoeial impurityZileuton USP Related Compound ACat. No. P-Z016-002CAS 171370-49-3
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Active ingredient · Zileuton family
Pharmaceutical analytical standardZileuton
Synonyms: 1-[1-(1-benzothiophen-2-yl)ethyl]-1-hydroxyurea, Zyflo, Leutrol, Zyflo CR, N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea, NSC 730712, NSC 759277, N-(1-(benzo(b)thiophen-2-yl)ethyl)-N-hydroxyurea, Urea, N-(1-benzo(b)thien-2-ylethyl)-N-hydroxy-, Ziluton, Zyflo Filmtab, Pharmakon1600-01505906
- Cat. No.
- P-Z016-001
- CAS
- 111406-87-2
- Alternative CAS
- N/A
- Formula
- C11H12N2O2S
- Molecular weight
- 236.29 g/mol
- Category
- Active ingredient (API)
An oral medicine for the prevention and long-term treatment of asthma, introduced in 1996: it inhibits 5-lipoxygenase, the enzyme that makes leukotrienes, instead of blocking their receptors like montelukast and zafirlukast.
Did you know?In mice it has also been studied against chronic myeloid leukaemia, alone or together with imatinib, and in an experimental model of dementia.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Zileuton family
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Pharmacopoeial impurityZileuton USP Related Compound CCat. No. P-Z016-004CAS 22720-75-8
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Isotopically labelledZileuton-d4Cat. No. P-Z016-006CAS 1189878-76-9![1-(benzo[b]thiophen-2-yl)ethanol](https://img.vitasanlabs.com/vsl-struct/P-Z016-007.svg?v=41e934f030)
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ImpurityN-Des(aminocarbonyl) ZileutonCat. No. P-Z016-008CAS 118564-89-9
ImpurityZileuton Impurity 1Cat. No. P-Z016-009CAS 1026256-93-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.