Family · Pharmaceutical analytical standards
Abacavir
An antiretroviral against HIV, a carbocyclic guanosine analogue that inhibits the virus's reverse transcriptase: developed in the 1980s by Robert Vince and Susan Daluge, it was approved in the United States in December 1998. This family brings together the active ingredient, pharmacopoeial impurities, metabolites, labelled standards, nitrosamines and other impurities.
Did you know?It is a classic example of pharmacogenetics: before treatment, DNA is checked for the HLA-B*5701 variant, linked to a hypersensitivity reaction, as confirmed in 2008 by the PREDICT-1 study.
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EDQM standards 3
The official European Pharmacopoeia standards for this family.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
