Family · Pharmaceutical analytical standards

Almotriptan

A triptan that stimulates serotonin 5-HT1B/1D receptors, narrowing the cranial blood vessels that dilate during an attack: it is used for acute migraine and was approved in the United States in 2001. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards, nitrosamines and other impurities.

Did you know?In 2009 it became the first triptan approved in the United States to treat migraine in adolescents aged 12 to 17 as well.

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Active ingredientAlmotriptanCat. No. P-A089-001CAS 154323-57-6

Active ingredientAlmotriptan MalateCat. No. P-A089-002CAS 181183-52-8

Pharmacopoeial impurityAlmotriptan EP Impurity B MalateCat. No. P-A089-003

Pharmacopoeial impurityAlmotriptan EP Impurity CCat. No. P-A089-004CAS 1018676-02-2

Pharmacopoeial impurityAlmotriptan EP Impurity D HemifumarateCat. No. P-A089-005CAS 1246860-65-0

Pharmacopoeial impurityAlmotriptan EP Impurity F MalateCat. No. P-A089-006

Isotopically labelledAlmotriptan-d6 MalateCat. No. P-A089-007

NitrosamineN,N-Dinitroso N-Desmethyl AlmotriptanCat. No. P-A089-008

NitrosamineN-Nitroso AlmotriptanCat. No. P-A089-009

NitrosamineN-Nitroso Almotriptan EP Impurity ACat. No. P-A089-010

NitrosamineN-Nitroso Almotriptan EP Impurity FCat. No. P-A089-011

NitrosamineN-Nitroso Almotriptan Hydrazine PrecursorCat. No. P-A089-012

NitrosamineN-Nitroso Almotriptan N,N-Didesmethyl ImpurityCat. No. P-A089-013

NitrosamineN-Nitroso(Indole) N-Desmethyl AlmotriptanCat. No. P-A089-015

NitrosamineN1,N2-Dinitroso Almotriptan EP Impurity BCat. No. P-A089-016

NitrosamineN1-Nitroso Almotriptan EP Impurity BCat. No. P-A089-017

NitrosamineN2-Nitroso Almotriptan EP Impurity BCat. No. P-A089-018

ImpurityN-Methyl-2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]propan-2-amineCat. No. P-A089-020CAS 1391053-74-9

Impurity4-(Pyrrolidin-1-ylsulfonylmethyl)anilineCat. No. P-A089-021CAS 334981-10-1

Impurity4-Chlorobutanal Dimethyl AcetalCat. No. P-A089-022CAS 29882-07-3

Impurity4-Chlorobutyraldehyde Diethyl AcetalCat. No. P-A089-023CAS 6139-83-9

Nitrosamine5-(Methylnitrosoamino)pentanalCat. No. P-A089-024CAS 59578-68-6

ImpurityAlmotriptan Hydrazine Precursor HClCat. No. P-A089-026CAS 334981-11-2

Pharmacopoeial impurity2-HydroxyalmotriptanCat. No. P-A089-028CAS 334981-13-4

ImpurityAlmotriptan Impurity 2Cat. No. P-A089-029

ImpurityAlmotriptan Impurity 3Cat. No. P-A089-030

ImpurityAlmotriptan Impurity 4Cat. No. P-A089-031CAS 334981-31-6

ImpurityAlmotriptan Impurity 5Cat. No. P-A089-032

ImpurityAlmotriptan Impurity 6 DihydrochlorideCat. No. P-A089-033

ImpurityAlmotriptan Impurity 7Cat. No. P-A089-034

NitrosamineAlmotriptan Impurity 8Cat. No. P-A089-035

ImpurityAlmotriptan N,N-Didesmethyl Impurity MalateCat. No. P-A089-036

Pharmacopoeial impurityAlmotriptan EP Impurity BCat. No. P-A089-038CAS 1330166-13-6

Pharmacopoeial impurityAlmotriptan N-OxideCat. No. P-A089-039CAS 603137-43-5

Impuritygamma-Aminobutyric Acid AlmotriptanCat. No. P-A089-040CAS 603137-41-3

ImpurityAlmotriptan Impurity 11Cat. No. P-A089-041CAS 1042449-29-5

ImpurityN-Desmethyl Almotriptan MalateCat. No. P-A089-042

ImpuritySpiro AlmotriptanCat. No. P-A089-043CAS 1309457-18-8

EDQM standards 1

The official European Pharmacopoeia standards for this family.

Reference substanceAlmotriptan malate CRSEDQM code Y0002144Family Almotriptan

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