Active ingredientAlmotriptan MalateCat. No. P-A089-002CAS 181183-52-8
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Active ingredient · Almotriptan family
Pharmaceutical analytical standardAlmotriptan
Synonyms: Almogran, NSC 760092, Pyrrolidine, 1-(((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)methyl)sulfonyl)-, Dimethyl(2-(5-((pyrrolidine-1-sulfonyl)methyl)-1H-indol-3-yl)ethyl)amine, Axert, N,N-dimethyl-2-(5-((pyrrolidin-1-ylsulfonyl)methyl)-1H-indol-3-yl)ethanamine
- Cat. No.
- P-A089-001
- CAS
- 154323-57-6
- Alternative CAS
- 181183-52-8 (malate)
- 154323-46-3 (hydrochloride)
- Formula
- C17H25N3O2S
- Molecular weight
- 335.47 g/mol
- Category
- Active ingredient (API)
A triptan that stimulates serotonin 5-HT1B/1D receptors, narrowing the cranial blood vessels that dilate during an attack: it is used for acute migraine and was approved in the United States in 2001.
Did you know?In 2009 it became the first triptan approved in the United States to treat migraine in adolescents aged 12 to 17 as well.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Almotriptan family
Active ingredientAlmotriptan MalateCat. No. P-A089-002CAS 181183-52-8
Pharmacopoeial impurityAlmotriptan EP Impurity B MalateCat. No. P-A089-003
Pharmacopoeial impurityAlmotriptan EP Impurity CCat. No. P-A089-004CAS 1018676-02-2
Pharmacopoeial impurityAlmotriptan EP Impurity D HemifumarateCat. No. P-A089-005CAS 1246860-65-0
Pharmacopoeial impurityAlmotriptan EP Impurity F MalateCat. No. P-A089-006
Isotopically labelledAlmotriptan-d6 MalateCat. No. P-A089-007
NitrosamineN,N-Dinitroso N-Desmethyl AlmotriptanCat. No. P-A089-008
NitrosamineN-Nitroso AlmotriptanCat. No. P-A089-009Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.