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Family · Pharmaceutical analytical standards

Aprepitant

An NK1 receptor antagonist that stops substance P from acting on the nerve centres that trigger vomiting. Approved in 2003 in Europe and the United States, it is used to prevent chemotherapy-induced nausea and vomiting. This family brings together the active ingredient, pharmacopoeial impurities, metabolites, labelled standards, nitrosamines and other impurities.

Did you know?It was also studied as a possible antidepressant: that project was dropped in 2003, a few months after the molecule had been approved as a medicine against vomiting.

AprepitantGo to the active ingredient →
AprepitantActive ingredientAprepitantCat. No. P-A176-001CAS 170729-80-3
Aprepitant-d4Isotopically labelledAprepitant-d4Cat. No. P-A176-010CAS 1133387-60-6

EDQM standards 1

The official European Pharmacopoeia standards for this family.

Reference substanceAprepitant CRSEDQM code Y0001825Family Aprepitant

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