Family · Pharmaceutical analytical standards
Atglistatin
A small molecule that selectively inhibits adipose triglyceride lipase (ATGL), the enzyme that starts the release of fatty acids from fat stores; described in 2013 by researchers in Graz, Austria, it is used as a research tool in metabolism. This family brings together the active ingredient, nitrosamines and other impurities.
Did you know?It blocks the mouse enzyme well but not the human one: in 2022 the same Graz group found that just three amino acids decide which species an inhibitor works on, and created one for the human enzyme.
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