Active ingredientAtglistatinCat. No. P-A206-001CAS 1469924-27-3
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Nitrosamine · Atglistatin family
Pharmaceutical analytical standardN2-Nitroso N2-Desmethyl Atglistatin
- Cat. No.
- P-A206-004
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C16H18N4O2
- Molecular weight
- 298.35 g/mol
- Category
- Nitrosamine
Family: Atglistatin
A small molecule that selectively inhibits adipose triglyceride lipase (ATGL), the enzyme that starts the release of fatty acids from fat stores; described in 2013 by researchers in Graz, Austria, it is used as a research tool in metabolism.
Did you know?It blocks the mouse enzyme well but not the human one: in 2022 the same Graz group found that just three amino acids decide which species an inhibitor works on, and created one for the human enzyme.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Atglistatin family
Active ingredientAtglistatinCat. No. P-A206-001CAS 1469924-27-3
NitrosamineN-Nitroso AtglistatinCat. No. P-A206-002
NitrosamineN1-Nitroso-N1-Desmethyl AtglistatinCat. No. P-A206-003
ImpurityDinitro N1-Desmethyl AtglistatinCat. No. P-A206-005
ImpurityDinitro N2-Desmethyl AtglistatinCat. No. P-A206-006
ImpurityN1-Desmethyl AtglistatinCat. No. P-A206-007
ImpurityN2-Desmethyl AtglistatinCat. No. P-A206-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.