Family · Pharmaceutical analytical standards
Avibactam
A beta-lactamase inhibitor with a non-beta-lactam structure (a diazabicyclooctane), approved in the United States in 2015 together with ceftazidime: it shields the antibiotic from the enzymes that resistant Gram-negative bacteria use to destroy it. This family brings together the active ingredient, labelled standards and other impurities.
Did you know?It binds the enzyme covalently but reversibly: when it lets go it has not been broken down, so it comes off intact and can block another beta-lactamase.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
