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Family · Pharmaceutical analytical standards

Bufexamac

A topical non-steroidal anti-inflammatory drug, used in creams for eczema, sunburn and itching and in suppositories for haemorrhoids; in 2010 the European Medicines Agency recommended its withdrawal because of the risk of allergic contact dermatitis. This family brings together the active ingredient and pharmacopoeial impurities.

Did you know?In 2011 a chemoproteomics study found that it specifically inhibits two epigenetic enzymes, the histone deacetylases HDAC6 and HDAC10: an old skin medicine turned research tool.

BufexamacGo to the active ingredient →
BufexamacActive ingredientBufexamacCat. No. P-B132-001CAS 2438-72-4

EDQM standards 5

The official European Pharmacopoeia standards for this family.

Reference substanceBufexamac CRSEDQM code B1156000Family Bufexamac

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