Family · Pharmaceutical analytical standards
Bufexamac
A topical non-steroidal anti-inflammatory drug, used in creams for eczema, sunburn and itching and in suppositories for haemorrhoids; in 2010 the European Medicines Agency recommended its withdrawal because of the risk of allergic contact dermatitis. This family brings together the active ingredient and pharmacopoeial impurities.
Did you know?In 2011 a chemoproteomics study found that it specifically inhibits two epigenetic enzymes, the histone deacetylases HDAC6 and HDAC10: an old skin medicine turned research tool.
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EDQM standards 5
The official European Pharmacopoeia standards for this family.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
