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Family · Pharmaceutical analytical standards

Colesevelam

A bile acid sequestrant: it binds bile acids in the gut and prevents their reabsorption, so the liver uses up LDL cholesterol to make new ones. It was approved in the US in 2000 for hypercholesterolaemia and later also for type 2 diabetes. This family brings together nitrosamines and other impurities.

Did you know?More than a molecule it is a network: a polyallylamine cross-linked with epichlorohydrin and then modified, which is neither absorbed nor metabolised and leaves the body through the gut.

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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.