NitrosamineN-Nitroso Colesevelam Decyl Aminoquat BromideCat. No. P-C241-002
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Impurity or related compound · Colesevelam family
Pharmaceutical analytical standardColesevelam Impurity 2
Synonyms: 6-Bromohexyl(trimethyl)azanium bromide, 6-bromo-N,N,N-trimethylhexan-1-aminium bromide, Ammonium, (6-bromohexyl)trimethyl-, bromide, Bromohexyltrimethylaminium bromide, Bromoquat, Colesevelam Bromoquat Impurity
- Cat. No.
- P-C241-007
- CAS
- 32765-81-4
- Alternative CAS
- 191086-27-8 (free base)
- Formula
- C9H21BrN·Br
- Molecular weight
- 303.08 g/mol
- Category
- Impurity or related compound
Family: Colesevelam
A bile acid sequestrant: it binds bile acids in the gut and prevents their reabsorption, so the liver uses up LDL cholesterol to make new ones. It was approved in the US in 2000 for hypercholesterolaemia and later also for type 2 diabetes.
Did you know?More than a molecule it is a network: a polyallylamine cross-linked with epichlorohydrin and then modified, which is neither absorbed nor metabolised and leaves the body through the gut.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Colesevelam family
NitrosamineN-Nitroso Colesevelam Decyl Aminoquat BromideCat. No. P-C241-002
ImpurityColesevelam Impurity 1Cat. No. P-C241-004CAS 2170771-70-5
ImpurityColesevelam Decyl Aminoquat Bromide HBrCat. No. P-C241-005CAS 2247938-20-9
ImpurityColesevelam Hydroxyquat ImpurityCat. No. P-C241-006CAS 676578-21-5
ImpurityColesevelam Impurity 3Cat. No. P-C241-008CAS 2247938-18-5
ImpurityColesevelam Methoxyquat ImpurityCat. No. P-C241-009CAS 863031-14-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.