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Family · Pharmaceutical analytical standards

Dantrolene

A muscle relaxant that acts directly on muscle, curbing calcium release through the ryanodine receptor; first described in 1967, it is the main medicine for malignant hyperthermia, a rare reaction to anaesthesia, and is also used for spasticity. This family brings together the active ingredient, pharmacopoeial impurities, metabolites, labelled standards and other impurities.

Did you know?Its effect against malignant hyperthermia was shown in the 1970s by South African anaesthetist Gaisford Harrison, in pigs that naturally carry the same genetic predisposition.

DantroleneGo to the active ingredient →
DantroleneActive ingredientDantroleneCat. No. P-D012-001CAS 7261-97-4
Dantrolene-d4Isotopically labelledDantrolene-d4Cat. No. P-D012-008CAS 2749234-17-9

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