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Family · Pharmaceutical analytical standards

Dimethyl Fumarate

An ester of fumaric acid taken by mouth for psoriasis, in Germany since 1994 in a mixture with other fumarates, and for relapsing multiple sclerosis, in the United States since 2013 and in Europe since 2014; in the body it becomes monomethyl fumarate. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards and other impurities.

Did you know?It all began with a hypothesis by the German chemist Walter Schweckendiek, who in 1959 blamed psoriasis on a disturbance of fumaric acid in the Krebs cycle: the theory did not hold up, the treatment did.

Dimethyl FumarateGo to the active ingredient →

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