Active ingredientDiphenhydramine HydrochlorideCat. No. P-D141-001CAS 147-24-0Family · Pharmaceutical analytical standards
Diphenhydramine
A first-generation antihistamine synthesised in 1943 at the University of Cincinnati, in George Rieveschl's laboratory; in 1946 it became the first prescription antihistamine approved in the United States. It is used for allergies and itching and, thanks to its sedative effect, as a sleep aid. This family brings together the active ingredient, pharmacopoeial impurities, metabolites, labelled standards, nitrosamines and other impurities.
Did you know?Rieveschl was looking for a medicine against muscle spasms. Years later, studies of its ability to block serotonin reuptake helped lead to the development of fluoxetine.
Go to the active ingredient →Active ingredientDiphenhydramine HydrochlorideCat. No. P-D141-001CAS 147-24-0
MetaboliteDiphenhydramine N-GlucuronideCat. No. P-D141-002CAS 137908-78-2
Isotopically labelledDiphenhydramine-d3Cat. No. P-D141-003CAS 170082-18-5
Isotopically labelledDiphenhydramine-d5Cat. No. P-D141-004CAS 1219908-66-3
Isotopically labelledDiphenhydramine-d5 HClCat. No. P-D141-005CAS 1219795-16-0
Isotopically labelledDiphenhydramine-d6 HClCat. No. P-D141-006CAS 1189986-72-8
Isotopically labelledN-Desmethyl Diphenhydramine-d3 HydrochlorideCat. No. P-D141-007CAS 1794759-12-8
Isotopically labelledN-Nitroso Diphenhydramine EP Impurity A-d5Cat. No. P-D141-008
NitrosamineN-Nitroso Diphenhydramine EP Impurity ACat. No. P-D141-009CAS 55855-43-1
NitrosamineN-Nitroso Diphenhydramine Impurity 1Cat. No. P-D141-010
NitrosamineN-Nitroso Diphenhydramine Impurity 2Cat. No. P-D141-011
Impurity2-(Benzhydryloxy)-N,N-dimethylacetamideCat. No. P-D141-012CAS 41858-14-4
ImpurityBenzhydryloxyacetic acidCat. No. P-D141-013CAS 21409-25-6
ImpurityDiphenhydramine Impurity 1Cat. No. P-D141-014
ImpurityDiphenhydramine Impurity 2Cat. No. P-D141-015
ImpurityDiphenhydramine Impurity 3Cat. No. P-D141-016CAS 524942-74-3
ImpurityDiphenhydramine Impurity 4Cat. No. P-D141-018CAS 71126-64-2
ImpurityDiphenhydramine MethiodideCat. No. P-D141-020CAS 14177-81-2
ImpurityDiphenhydramine N-OxideCat. No. P-D141-021CAS 3922-74-5
ImpurityDiphenhydramine N-Oxide HydrochlorideCat. No. P-D141-022CAS 13168-00-8
Pharmacopoeial impurityDiphenhydramine USP Related Compound BCat. No. P-D141-023CAS 19574-66-4No product matches your search.
EDQM standards 2
The official European Pharmacopoeia standards for this family.
Reference substanceDiphenhydramine hydrochloride CRSEDQM code D2600000Family Diphenhydramine
ImpurityDiphenhydramine impurity A CRSEDQM code Y0000135Family DiphenhydramineNeed a molecule you cannot find?
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