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Family · Pharmaceutical analytical standards

Encorafenib

An oral anticancer drug that blocks mutated BRAF protein: it is used for melanoma with a BRAF V600 mutation and, since 2020 in the United States, with cetuximab for metastatic colorectal cancer with the BRAF V600E mutation. This family brings together the active ingredient, labelled standards and other impurities.

Did you know?The code V600E means that in the BRAF protein the amino acid valine at position 600 is replaced by glutamic acid: a single change that keeps the cell's growth signal permanently switched on.

EncorafenibGo to the active ingredient →
EncorafenibActive ingredientEncorafenibCat. No. P-E045-001CAS 1269440-17-6
Encorafenib-d7Isotopically labelledEncorafenib-d7Cat. No. P-E045-002CAS 2413673-15-9

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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.