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Family · Pharmaceutical analytical standards

Everolimus

An mTOR inhibitor derived from sirolimus (rapamycin): approved in the United States in 2009 for advanced kidney cancer and in 2010 against kidney transplant rejection, it is also used in some breast and neuroendocrine tumours and in coronary stents. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards and other impurities.

Did you know?The rapamycin it derives from comes from a bacterium found in a soil sample collected on Easter Island (Rapa Nui) during a Canadian expedition in 1964-65: the name honours the island.

EverolimusGo to the active ingredient →
EverolimusActive ingredientEverolimusCat. No. P-E143-001CAS 159351-69-6
Everolimus-d4Isotopically labelledEverolimus-d4Cat. No. P-E143-007CAS 1338452-54-2

EDQM standards 2

The official European Pharmacopoeia standards for this family.

Reference substanceEverolimus CRSEDQM code Y0002048Family Everolimus

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