Family · Pharmaceutical analytical standards
Flumatinib
A second-generation BCR-ABL tyrosine kinase inhibitor, approved in China in late 2019 for adults with Philadelphia chromosome-positive chronic myeloid leukaemia in the chronic phase. This family brings together the active ingredient, labelled standards, nitrosamines and other impurities.
Did you know?It is a derivative of imatinib: compared with its parent drug, one of its benzene rings is replaced by a pyridine and a trifluoromethyl group is added, which make additional contacts with the target kinase.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
