Family · Pharmaceutical analytical standards
Idelalisib
An oral inhibitor of PI3K delta, an enzyme found in normal and malignant B lymphocytes. Approved in the United States in July 2014, it was the first drug of the PI3K inhibitor class; it is used mainly in chronic lymphocytic leukaemia. This family brings together the active ingredient, metabolites, labelled standards, nitrosamines and other impurities.
Did you know?It works on two fronts: it switches off B-cell receptor signals and blocks the chemical calls, such as those of the CXCR4 and CXCR5 receptors, that guide these cells to their hideouts in the lymph nodes and bone marrow.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
