Family · Pharmaceutical analytical standards
Metamizole
A pyrazolone analgesic and antipyretic, synthesised in 1920 and first marketed in Germany in 1922; used for acute pain and high fever, it is a prodrug that the body turns into the active metabolite 4-MAA. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards, nitrosamines and other impurities.
Did you know?It descends from antipyrine, which German chemist Ludwig Knorr obtained in the 1880s while looking for quinine derivatives: the "mother" of all modern antipyretics.
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EDQM standards 3
The official European Pharmacopoeia standards for this family.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
