Active ingredientMetamizole Magnesium SaltCat. No. P-M069-001CAS 6150-97-6
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Impurity or related compound · Metamizole family
Pharmaceutical analytical standardMetamizole Impurity 11
Synonyms: 5-Methyl-1-nitroso-2-phenylpyrazol-3-one
- Cat. No.
- P-M069-040
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C10H9N3O2
- Molecular weight
- 203.20 g/mol
- Category
- Impurity or related compound
Family: Metamizole
A pyrazolone analgesic and antipyretic, synthesised in 1920 and first marketed in Germany in 1922; used for acute pain and high fever, it is a prodrug that the body turns into the active metabolite 4-MAA.
Did you know?It descends from antipyrine, which German chemist Ludwig Knorr obtained in the 1880s while looking for quinine derivatives: the "mother" of all modern antipyretics.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Metamizole family
Active ingredientMetamizole Magnesium SaltCat. No. P-M069-001CAS 6150-97-6
Active ingredientMetamizole Sodium MonohydrateCat. No. P-M069-002CAS 5907-38-0
Active ingredientMetamizole Sodium SaltCat. No. P-M069-003CAS 68-89-3
Pharmacopoeial impurityMetamizole EP Impurity ACat. No. P-M069-004CAS 1672-58-8
Pharmacopoeial impurityMetamizole EP Impurity BCat. No. P-M069-005CAS 83-07-8
Isotopically labelledMetamizole EP Impurity B d-3Cat. No. P-M069-006CAS 68229-55-0
Pharmacopoeial impurityMetamizole EP Impurity CCat. No. P-M069-007CAS 519-98-2
Pharmacopoeial impurityMetamizole EP Impurity C HydrochlorideCat. No. P-M069-008CAS 856307-27-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.