Active ingredientMethotrexateCat. No. P-M085-001CAS 59-05-2Family · Pharmaceutical analytical standards
Methotrexate
An antifolate that blocks the enzyme dihydrofolate reductase, in use since the late 1940s: born to fight childhood leukaemia, today it is used in oncology and, at low doses, for rheumatoid arthritis and psoriasis. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards, nitrosamines and other impurities.
Did you know?In 1956 Min Chiu Li and Roy Hertz used it against choriocarcinoma, a cancer of the placenta: some patients with metastases were completely cured, the first time chemotherapy had cured a metastatic cancer.
Go to the active ingredient →Active ingredientMethotrexateCat. No. P-M085-001CAS 59-05-2
Active ingredientMethotrexate DisodiumCat. No. P-M085-002CAS 7413-34-5
Pharmacopoeial impurityMethotrexate EP Impurity DCat. No. P-M085-003CAS 5623-18-7
Pharmacopoeial impurityMethotrexate EP Impurity A HydrochlorideCat. No. P-M085-004CAS 73978-41-3
Pharmacopoeial impurityMethotrexate EP Impurity ACat. No. P-M085-005CAS 945-24-4
Pharmacopoeial impurityMethotrexate EP Impurity BCat. No. P-M085-006CAS 54-62-6
Pharmacopoeial impurityMethotrexate EP Impurity CCat. No. P-M085-007CAS 2410-93-7
Pharmacopoeial impurityMethotrexate EP Impurity ECat. No. P-M085-008CAS 19741-14-1
Pharmacopoeial impurityMethotrexate EP Impurity E HemihydrochlorideCat. No. P-M085-009CAS 70844-48-3
Pharmacopoeial impurityMethotrexate EP Impurity F Disodium SaltCat. No. P-M085-010
Pharmacopoeial impurityMethotrexate EP Impurity GCat. No. P-M085-011CAS 2519848-42-9
Pharmacopoeial impurityMethotrexate EP Impurity G EnantiomerCat. No. P-M085-013
Pharmacopoeial impurityMethotrexate EP Impurity HCat. No. P-M085-014CAS 67022-39-3
Pharmacopoeial impurityMethotrexate EP Impurity ICat. No. P-M085-015CAS 66147-29-3
Pharmacopoeial impurityMethotrexate EP Impurity I EnantiomerCat. No. P-M085-016CAS 440339-37-7
Pharmacopoeial impurityMethotrexate EP Impurity I Sodium Salt (Methotrexate-1-Monomethyl Ester Sodium Salt)Cat. No. P-M085-017
Pharmacopoeial impurityMethotrexate EP Impurity JCat. No. P-M085-018CAS 34378-65-9
Pharmacopoeial impurityMethotrexate EP Impurity LCat. No. P-M085-019CAS 52980-68-4
Pharmacopoeial impurityMethotrexate EP Impurity L Disodium saltCat. No. P-M085-020CAS 57444-71-0
Pharmacopoeial impurityMethotrexate EP Impurity L EnantiomerCat. No. P-M085-021CAS 52030-86-1
Isotopically labelledMethotrexate EP Impurity B-d4Cat. No. P-M085-024
Isotopically labelledMethotrexate EP Impurity F-13C-d3 Disodium SaltCat. No. P-M085-025
Isotopically labelledMethotrexate Impurity 7-d3Cat. No. P-M085-026
Isotopically labelledMethotrexate-d3Cat. No. P-M085-028CAS 432545-63-6
Isotopically labelledMethotrexate-d3 Diglutamate TrifluoroacetateCat. No. P-M085-029
Isotopically labelledMethotrexate-d3 Heptaglutamate TrifluoroacetateCat. No. P-M085-030
Isotopically labelledMethotrexate-d3 Triglutamate TrifluoroacetateCat. No. P-M085-032
Isotopically labelledN-Nitroso Methotrexate EP Impurity B-d4Cat. No. P-M085-033
Isotopically labelledN-Nitroso Methotrexate-13C-d3Cat. No. P-M085-034
NitrosamineMethotrexate diethyl ester Nitroso ImpurityCat. No. P-M085-035
NitrosamineN-Nitroso Methotrexate Impurity 1Cat. No. P-M085-037
NitrosamineN-Nitroso Methotrexate Impurity 2Cat. No. P-M085-038
NitrosamineN-Nitroso Methotrexate Impurity 3Cat. No. P-M085-039
NitrosamineN-Nitroso Methotrexate Impurity 4Cat. No. P-M085-040
NitrosamineN,N-Dinitroso Methotrexate EP Impurity LCat. No. P-M085-041
NitrosamineN-Nitroso MethotrexateCat. No. P-M085-042
NitrosamineN-Nitroso Methotrexate EP Impurity BCat. No. P-M085-043
NitrosamineN-Nitroso Methotrexate EP Impurity LCat. No. P-M085-045
NitrosamineN-Nitroso Methotrexate Impurity 5Cat. No. P-M085-046
Pharmacopoeial impurityMethotrexate EP Impurity G HydrochlorideCat. No. P-M085-047
Pharmacopoeial impurity(R)-MethotrexateCat. No. P-M085-048CAS 51865-79-3
Impurity2,4-Diamino-7-PteridinemethanolCat. No. P-M085-049CAS 881-33-4
Impurity4,5,6-Triaminopyrimidin-2(1h)-oneCat. No. P-M085-050CAS 22715-34-0
Impurity4-(Methylamino)benzoic acidCat. No. P-M085-051CAS 10541-83-0
Impurity6-Methylpteridine-2,4-diamineCat. No. P-M085-052CAS 708-74-7
Impurity7-(Bromomethyl)pteridine-2,4-diamineCat. No. P-M085-053CAS 2801801-56-7
Impurity7-Hydroxy MethotrexateCat. No. P-M085-054CAS 5939-37-7
Impurity7-MethotrexateCat. No. P-M085-056CAS 52980-66-2
ImpurityMethotrexate Impurity 2Cat. No. P-M085-057CAS 2378-95-2
ImpurityLysine-methotrexateCat. No. P-M085-058CAS 80407-56-3
ImpurityMethotrexate alpha-tert-butyl esterCat. No. P-M085-059CAS 79640-70-3
ImpurityMethotrexate Diamide ImpurityCat. No. P-M085-061
ImpurityMethotrexate Diethyl EsterCat. No. P-M085-062CAS 43170-88-3
ImpurityMethotrexate DiglutamateCat. No. P-M085-063CAS 41600-13-9
ImpurityMethotrexate Dimethylamide (Racemic Mixture)Cat. No. P-M085-064
ImpurityMethotrexate Heptaglutamate TrifluoroacetateCat. No. P-M085-066
ImpurityMethotrexate Impurity 3 HydrochlorideCat. No. P-M085-067
ImpurityMethotrexate Impurity 4Cat. No. P-M085-068
ImpurityMethotrexate Impurity 5Cat. No. P-M085-069
ImpurityMethotrexate Impurity 6 TrifluoroacetateCat. No. P-M085-070
ImpurityMethotrexate Impurity 7Cat. No. P-M085-071CAS 60388-53-6
ImpurityMethotrexate Tetraglutamate TrifluoroacetateCat. No. P-M085-072
ImpurityMethotrexate Impurity 8Cat. No. P-M085-074CAS 728946-34-7
ImpurityTetraaminopyrimidine sulfateCat. No. P-M085-075CAS 5392-28-9No product matches your search.
EDQM standards 5
The official European Pharmacopoeia standards for this family.
Reference substanceMethotrexate CRSEDQM code M1000000Family MethotrexateImpurityMethotrexate impurity C CRSEDQM code Y0000663Family MethotrexateImpurityMethotrexate impurity D CRSEDQM code M1000008Family MethotrexateImpurityMethotrexate impurity E CRSEDQM code Y0000664Family MethotrexateNeed a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.