Family · Pharmaceutical analytical standards
Neostigmine
A cholinesterase inhibitor synthesised in 1931 by Aeschlimann and Reinert, a simplified version of physostigmine: it is used for myasthenia gravis and to reverse the effect of muscle relaxants at the end of anaesthesia. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards, nitrosamines and other impurities.
Did you know?In 1934 Scottish physician Mary Walker found that physostigmine briefly relieved myasthenia gravis, 'the miracle at St Alfege's', named after her London hospital; in 1935 she showed the same benefit with neostigmine.
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EDQM standards 3
The official European Pharmacopoeia standards for this family.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
