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Family · Pharmaceutical analytical standards

Ondansetron

A selective serotonin 5-HT3 receptor antagonist developed in London in the mid-1980s and approved in the United States in 1991. It prevents nausea and vomiting caused by chemotherapy and surgery and is on the WHO List of Essential Medicines. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards and other impurities.

Did you know?Chemotherapy makes enterochromaffin cells in the gut release serotonin, which stimulates the vagus nerve and triggers the vomiting reflex: ondansetron works mainly by blocking this signal in the periphery.

OndansetronGo to the active ingredient →
OndansetronActive ingredientOndansetronCat. No. P-O023-001CAS 99614-02-5
ImidazolePharmacopoeial impurityImidazoleCat. No. P-O023-004CAS 288-32-4

EDQM standards 9

The official European Pharmacopoeia standards for this family.

Reference substanceImidazole CRSEDQM code I0086000Family Ondansetron

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