Family · Pharmaceutical analytical standards
Pravastatin
A statin that lowers LDL cholesterol by blocking the enzyme HMG-CoA reductase, derived from compactin, the first statin, isolated by Akira Endo from the fungus Penicillium citrinum; in use since 1989. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards and other impurities.
Did you know?It was first found in the urine of a dog, during studies on how compactin is metabolised; today it is made by letting microorganisms such as Streptomyces carbophilus add a hydroxyl group to compactin.
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EDQM standards 2
The official European Pharmacopoeia standards for this family.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
