Active ingredientPravastatin SodiumCat. No. P-P172-001CAS 81131-70-6
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Stable isotope labelled · Pravastatin family
Pharmaceutical analytical standardPravastatin-13C-d3 Sodium Salt
- Cat. No.
- P-P172-015
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C22¹³CH32D3NaO7
- Molecular weight
- 450.53 g/mol
- Category
- Stable isotope labelled
Family: Pravastatin
A statin that lowers LDL cholesterol by blocking the enzyme HMG-CoA reductase, derived from compactin, the first statin, isolated by Akira Endo from the fungus Penicillium citrinum; in use since 1989.
Did you know?It was first found in the urine of a dog, during studies on how compactin is metabolised; today it is made by letting microorganisms such as Streptomyces carbophilus add a hydroxyl group to compactin.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Pravastatin family
Active ingredientPravastatin SodiumCat. No. P-P172-001CAS 81131-70-6
Pharmacopoeial impurity6'-EpipravastatinCat. No. P-P172-002CAS 250737-12-3
Pharmacopoeial impurityPravastatin EP Impurity A Sodium SaltCat. No. P-P172-003CAS 81176-41-2
Pharmacopoeial impurityPravastatin EP Impurity B Sodium SaltCat. No. P-P172-004CAS 722504-46-3
Pharmacopoeial impurityPravastatin EP Impurity C Sodium SaltCat. No. P-P172-005CAS 159225-12-4
Pharmacopoeial impurityPravastatin EP Impurity DCat. No. P-P172-006CAS 85956-22-5
Pharmacopoeial impurityPravastatin EP Impurity E Sodium SaltCat. No. P-P172-007CAS 722504-45-2
Pharmacopoeial impurityPravastatin EP Impurity F Sodium SaltCat. No. P-P172-008CAS 151061-28-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.