Active ingredientProguanil HydrochlorideCat. No. P-P202-001CAS 637-32-1Family · Pharmaceutical analytical standards
Proguanil
An antimalarial of the biguanide class, introduced in 1945 after research by the British chemists Frank Rose and Frank Curd: it is also used together with atovaquone to prevent and treat malaria. This family brings together the active ingredient, pharmacopoeial impurities and other impurities.
Did you know?It is a prodrug: the liver converts it into cycloguanil, which blocks the parasite's dihydrofolate reductase enzyme. When combined with atovaquone, however, it seems to act through a different mechanism.
Go to the active ingredient →Active ingredientProguanil HydrochlorideCat. No. P-P202-001CAS 637-32-1
Pharmacopoeial impurityProguanil EP Impurity C HydrochlorideCat. No. P-P202-003CAS 13590-98-2
Pharmacopoeial impurityProguanil EP Impurity D HydrochlorideCat. No. P-P202-004CAS 35708-82-8
Pharmacopoeial impurityProguanil EP Impurity ECat. No. P-P202-005CAS 1482-62-8
ImpurityProguanil Impurity 1 HydrochlorideCat. No. P-P202-007
Impurity1-Cyano-3-(1-methylethyl)guanidineCat. No. P-P202-008CAS 44830-55-9
Active ingredientProguanilCat. No. P-P202-009CAS 500-92-5No product matches your search.
EDQM standards 3
The official European Pharmacopoeia standards for this family.
Reference substanceProguanil hydrochloride CRSEDQM code Y0001901Family Proguanil
ImpurityProguanil impurity B CRSEDQM code Y0001909Family ProguanilNeed a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.