Family · Pharmaceutical analytical standards
Ribociclib
An inhibitor of the kinases CDK4 and CDK6, which drive the division of tumour cells: approved in the United States in 2017, together with hormone therapy, for advanced hormone receptor-positive, HER2-negative breast cancer. This family brings together the active ingredient, labelled standards, nitrosamines and other impurities.
Did you know?Its targets work together with cyclins, proteins discovered in 1982 by Tim Hunt while studying fertilised sea urchin eggs: a discovery rewarded with the Nobel Prize in 2001.
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