Family · Pharmaceutical analytical standards

Rivastigmine

A cholinesterase inhibitor, a semi-synthetic derivative of physostigmine, that raises acetylcholine in the brain: in use since 1997 for mild to moderate dementia in Alzheimer's disease and, later, in Parkinson's disease. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards, nitrosamines and other impurities.

Did you know?In 2006 it became the first medicine approved for dementia associated with Parkinson's disease, and in 2007, as a transdermal patch, the first dementia treatment applied to the skin.

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Active ingredientRivastigmine Hydrogen TartrateCat. No. P-R073-001CAS 129101-54-8

Pharmacopoeial impurityRivastigmine EP Impurity DCat. No. P-R073-003CAS 415973-05-6

Pharmacopoeial impurity(R)-Rivastigmine D-TartrateCat. No. P-R073-004

Pharmacopoeial impurityRivastigmine EP Impurity ACat. No. P-R073-005CAS 139306-10-8

Pharmacopoeial impurityRivastigmine EP Impurity A L-TartrateCat. No. P-R073-006

Pharmacopoeial impurityRivastigmine EP Impurity B (as Racemate Hydrochloride)Cat. No. P-R073-007CAS 105601-13-6

Pharmacopoeial impurityRivastigmine EP Impurity BCat. No. P-R073-008CAS 1230021-28-9

Pharmacopoeial impurityRivastigmine EP Impurity B L-TartrateCat. No. P-R073-010

Pharmacopoeial impurityRivastigmine EP Impurity CCat. No. P-R073-011CAS 855300-09-3

Pharmacopoeial impurityRivastigmine EP Impurity E (as Racemate)Cat. No. P-R073-012CAS 948051-93-2

Pharmacopoeial impurityRivastigmine EP Impurity GCat. No. P-R073-014CAS 23308-82-9

Pharmacopoeial impurityRivastigmine EP Impurity HCat. No. P-R073-015CAS 586-37-8

Pharmacopoeial impurityRivastigmine Hydrogen Tartrate EP Impurity E HClCat. No. P-R073-016

Pharmacopoeial impurityRivastigmine Hydrogen Tartrate EP Impurity F HClCat. No. P-R073-018

Pharmacopoeial impurityRivastigmine USP Related Compound ACat. No. P-R073-019CAS 32634-68-7

Pharmacopoeial impurityRivastigmine USP Related Compound BCat. No. P-R073-020CAS 25081-93-0

Pharmacopoeial impurityRivastigmine USP Related Compound FCat. No. P-R073-021CAS 1346602-84-3

Isotopically labelled(R)-Rivastigmine EP Impurity A-d3Cat. No. P-R073-022

Isotopically labelled(R)-Rivastigmine EP Impurity A-d6Cat. No. P-R073-023

Isotopically labelledRivastigmine EP Impurity A-d3Cat. No. P-R073-025

Isotopically labelledRivastigmine EP Impurity A-d6Cat. No. P-R073-026CAS 1217706-31-4

Isotopically labelledRivastigmine-d6 Hydrogen TartrateCat. No. P-R073-027CAS 194930-00-2

NitrosamineN-Nitroso Rivastigmine Hydrogen Tartrate EP Impurity ECat. No. P-R073-028

Impurity(RS)-Rivastigmine 2-IsomerCat. No. P-R073-029CAS 1346242-34-9

ImpurityRivastigmine Impurity 1Cat. No. P-R073-030CAS 1369779-38-3

Active ingredient(S)-RivastigmineCat. No. P-R073-031CAS 123441-03-2

Impurity(S)-Rivastigmine Impurity 2 Di-p-toluoyl-tartrateCat. No. P-R073-032CAS 2580175-95-5

Impurity2-[(1S)-1-aminoethyl]phenol hydrochlorideCat. No. P-R073-033CAS 2829292-65-9

ImpurityRivastigmine Impurity 3Cat. No. P-R073-034CAS 1213234-35-5

ImpurityRivastigmine Impurity 4Cat. No. P-R073-035CAS 1346242-29-2

ImpurityRivastigmine Impurity 5Cat. No. P-R073-036CAS 1346242-30-5

ImpurityRivastigmine Impurity 6Cat. No. P-R073-037CAS 1213234-40-2

ImpurityRivastigmine Impurity 7Cat. No. P-R073-038CAS 105601-05-6

Impurity4-[(1S)-1-(Dimethylamino)ethyl]phenolCat. No. P-R073-039CAS 1360535-15-4

Impurity4-[(1S)-1-Aminoethyl]phenolCat. No. P-R073-040CAS 221670-72-0

ImpurityDiethyl RivastigmineCat. No. P-R073-041CAS 1230021-34-7

ImpurityN-Desmethyl RivastigmineCat. No. P-R073-042CAS 1070660-34-2

ImpurityN-Methyl Rivastigmine ChlorideCat. No. P-R073-043CAS 3063998-82-0

Impurityrac-RivastigmineCat. No. P-R073-044CAS 105601-20-5

Impurityrac-Rivastigmine HClCat. No. P-R073-045CAS 105601-14-7

ImpurityRivastigmine Carbamate ImpurityCat. No. P-R073-046CAS 1346242-31-6

ImpurityRivastigmine Ether ImpurityCat. No. P-R073-047CAS 1346242-32-7

ImpurityRivastigmine Ether Impurity HClCat. No. P-R073-048

ImpurityRivastigmine Impurity 8Cat. No. P-R073-049

ImpurityRivastigmine Impurity 9Cat. No. P-R073-050

ImpurityRivastigmine Impurity 10 MandelateCat. No. P-R073-051CAS 1213234-38-8

ImpurityRivastigmine Impurity 11Cat. No. P-R073-052CAS 1213234-37-7

ImpurityRivastigmine Impurity 12Cat. No. P-R073-053CAS 63720-38-7

ImpurityRivastigmine Impurity 13Cat. No. P-R073-054

ImpurityRivastigmine Impurity 14Cat. No. P-R073-055

ImpurityRivastigmine Impurity 15Cat. No. P-R073-056

ImpurityRivastigmine Impurity 16 HydrochlorideCat. No. P-R073-057

ImpurityRivastigmine Impurity 17 HydrochlorideCat. No. P-R073-058

ImpurityRivastigmine Impurity 18 IodideCat. No. P-R073-059

ImpurityRivastigmine Impurity 19Cat. No. P-R073-060

ImpurityRivastigmine N-Oxide HClCat. No. P-R073-061

EDQM standards 3

The official European Pharmacopoeia standards for this family.

Structure not applicable: mixtureFor system suitabilityRivastigmine for system suitability CRSEDQM code Y0001485Family Rivastigmine

Reference substanceRivastigmine hydrogen tartrate CRSEDQM code Y0001516Family Rivastigmine

ImpurityRivastigmine impurity D CRSEDQM code Y0001515Family Rivastigmine

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