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Family · Pharmaceutical analytical standards

Teriflunomide

An immunomodulator that blocks the enzyme dihydroorotate dehydrogenase, slowing the de novo synthesis of pyrimidines, building blocks of DNA and RNA: it was approved in the US in 2012 and in the European Union in 2013 for multiple sclerosis. This family brings together labelled standards, nitrosamines and other impurities.

Did you know?It is the main active metabolite of leflunomide, an older drug: about 70% of leflunomide turns into teriflunomide in the body, simply by the opening of an isoxazole ring.

EDQM standards 3

The official European Pharmacopoeia standards for this family.

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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.