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Family · Pharmaceutical analytical standards

Tezacaftor

A CFTR protein modulator for cystic fibrosis, approved in 2018 in the United States and the European Union together with ivacaftor, and since 2019 (in the US) also in a triple combination with elexacaftor and ivacaftor. This family brings together the active ingredient, metabolites, labelled standards and other impurities.

Did you know?It is a 'corrector': it helps the CFTR protein altered by the F508del mutation fold into the right shape and reach the cell surface, where it can work.

TezacaftorGo to the active ingredient →
TezacaftorActive ingredientTezacaftorCat. No. P-T080-001CAS 1152311-62-0
Tezacaftor-d4Isotopically labelledTezacaftor-d4Cat. No. P-T080-004CAS 1961280-24-9
TezampanelImpurityTezampanelCat. No. P-T080-007CAS 154652-83-2
TezosentanImpurityTezosentanCat. No. P-T080-008CAS 180384-57-0

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