Family · Pharmaceutical analytical standards
Tezacaftor
A CFTR protein modulator for cystic fibrosis, approved in 2018 in the United States and the European Union together with ivacaftor, and since 2019 (in the US) also in a triple combination with elexacaftor and ivacaftor. This family brings together the active ingredient, metabolites, labelled standards and other impurities.
Did you know?It is a 'corrector': it helps the CFTR protein altered by the F508del mutation fold into the right shape and reach the cell surface, where it can work.
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