Family · Pharmaceutical analytical standards
Tolnaftate
A topical antifungal of the thiocarbamate class, discovered in Japan in 1962 by chemist Teruhisa Noguchi and used against athlete's foot, ringworm and other skin fungal infections; in most countries it is sold over the counter. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards, nitrosamines and other impurities.
Did you know?It is not an azole: like terbinafine it appears to block squalene epoxidase, an enzyme fungi need to make the ergosterol of their membranes, and it is especially useful against ringworm caught from pets.
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EDQM standards 2
The official European Pharmacopoeia standards for this family.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
