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Family · Pharmaceutical analytical standards

Tolnaftate

A topical antifungal of the thiocarbamate class, discovered in Japan in 1962 by chemist Teruhisa Noguchi and used against athlete's foot, ringworm and other skin fungal infections; in most countries it is sold over the counter. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards, nitrosamines and other impurities.

Did you know?It is not an azole: like terbinafine it appears to block squalene epoxidase, an enzyme fungi need to make the ergosterol of their membranes, and it is especially useful against ringworm caught from pets.

TolnaftateGo to the active ingredient →
TolnaftateActive ingredientTolnaftateCat. No. P-T155-001CAS 2398-96-1
Tolnaftate-d7Isotopically labelledTolnaftate-d7Cat. No. P-T155-006CAS 1329835-64-4
DonsImpurityDonsCat. No. P-T155-011CAS 31034-03-4

EDQM standards 2

The official European Pharmacopoeia standards for this family.

Reference substanceTolnaftate CRSEDQM code T1707000Family Tolnaftate

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