Pharmacopoeial impurityTolnaftate EP Impurity ACat. No. P-T155-002CAS 135-19-3
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Active ingredient · Tolnaftate family
Pharmaceutical analytical standardTolnaftate
Synonyms: O-naphthalen-2-yl N-methyl-N-(3-methylphenyl)carbamothioate, Tolnaphthate, Tinactin, Sporiline, Tinaderm, Tolsanil, Dermoxin, Focusan, Aftate, Pitrex, Naphthiomate T, Phytoderm, Timoped, Tritin, HI-Alazin, Separin, m,N-Dimethylthiocarbanilic acid O-2-naphthyl ester, O-Naphthalen-2-yl N-Methyl-N-(3-Methylphenyl)Thiocarbamate, Methyl (3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester, Carbamothioic acid, methyl(3-methylphenyl)-, O-2-naphthalenyl ester, Carbanilic acid, m,N-dimethylthio-, O-2-naphthyl ester, Fungus Relief, NSC 233648, N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide, Genaspor, Ting, Ony Clear, Purder N, Tolnaftat, Miconatate, Tolmaftate, Absorbine, Blistex, Fungifoam, Tineacide, Tolnafate, ProClearz, Tinaderm plus, Antifungal Foot, Sanafitil Crema, Tritolnacide S, TriTolnacide C, Nail Renew, Silka Antifungal, Toe Fungus, Winco Antifungal, Molecular AF, Micotrin AL, Nail Renu, Antifungal Liquid, Clarus Antifungal, Hi Vetic, Kiss Fungi-Gone, Meijer Antifungal, Mycozyl AL, Ongo-Fin, Target Antifungal, Tolnafi-AL, Conazol antifungal, Smooth AF, Dg Athletes Foot, Bengama Antifungal, Formula 3, Fungablend 10, Sunmark Antifungal, Tinactin Deodorant, Dr. Anti Fungus, Gadaderm Antifungal, Tinactin Antifungal, Equate Liquid Foot, Foot Works Healthy, Nail Renew Patches, Tinactin Jock Itch, Toe Area Treatment, Fungal Nail Patches, iBeaLee Nali liquid, KERACTIL Plus, Micomitin Antifungal, Homehealth Antifungal, Canespies, Equate Athletes Foot, iBealee Nail Patches, Keractil, Formula 7 THEGEL, HC Max Anti-Fungal, Dr. Gs Clear Nail, Flawless nails, Funginix af, Hongosan dsp, Family Care Antifungal, Opti-Nail 2-in-1, Flexitol Medicated Foot, Nail fungus set, Nekvnro FUNGAL NAIL, Walgreens Athletes Foot, Rite Aid Athletes Foot, Skin tag set, Athletes Foot Antifungal, Dg Health Athletes Foot, Personal Care Antifungal, Xtracare Antifungal Foot, Fungal nail renew, Forticept Antifungal Balm, Lotrimin Daily Prevention, Quality Choice Antifungal, Western Family Antifungal, Skinheal antifungal, CVS Health Athletes Foot, Bio-scriptives Extreme AF, Family Wellness Antifungal, ProClearz Laser Antifungal, Dermfree fungi nail, FUHOP Fungal Nail Liquid, Fuhop skin tag set, HC Max For Athletes Foot, Liquid Antifungal Treatment, Relispray Antifungal Liquid, FUHOP Fungal Nail Patches, FUHOP Wart Remover Liquid, Healmusz fungal nail, IZKUT Fungal Nail Patches, Skapemed skin repair, Accallo Fungal Nail Patches, Cidacin Antifungal Treatment, Meijer Athletes Foot Liquid, Nailene Antifungal Treatment, Sokth Multi-PurposeTreatment, Hermon antifungal bar, Fungicure Anti-Fungal Liquid, Fuhop nail fungus set, Dr Canuso Fungal Nail Eraser, Foot Works Healthy Antifungal, Lotrimin Daily Prevention Deo, FungiFree Fungal Nail Patches, Dr. Canuso Foot Repair Serum, First Aid Antifungal Medicated, AVON HeXashield Athletes Foot, Woodwards Mycocide Clinical NS, ANTIFUNGAL For Athletes Foot, Dermatool Fungal Nail Treatment, Nekvnro Multi-Purpose Treatment, UKVOA Toenail Fungus Treatment, Alveora FOOT ODOR PROBIOTIC, Defense Antifungal Medicated Bar, Lotrimin Daily Prevent Deodorant, Smart Sense Tolnftate Antifungal, HEALMUSZ Multi-PurposeTreatment, Ukova foot odor probiotic, Alvera NAIL FUNGUS TREATMENT, FIobow FUNGAL NAIL TREATMENT, Alveora NAIL FUNGUS TREATMENT, Antifungal Liquid Maximum Strength, Folupia fungal nail renewal, GoodSense Athletes Foot Antifungal, Lucky super soft antifungal, Maximum Strength Antifungal Liquid, Signature Athletes Foot Antifungal, Phytozine ringworm treatment, SUAI Fungus Nail Treatment Liquid, Funginix jock itch treatment, Healmusz foot odor probiotic, Proclearz Professional Fungal Shield, Sylvirene fungal nail renewal, CVS Health Antifungal Anthletes Foot, Antifungal medicated body wash, Kerasal for Athletes Foot Silky Clear, Kiss Fungi-gone Anti-fungal Treatment, Qsoowis multi-purpose treatment, Reinreude multi-purpose treatment, Signature Care Athletes Foot Antifungal, Gold Mountain Beauty Fungal Nail Eliminator, Gold Mountain Beauty Intensive Repair Serum, Walgreens Medicated Antifungal Athletes Foot, Dr. Scholls Instant Cool Athletes Foot Wipes, Barielle Fungus Rx Maximum Strength Anti-fungal, Walgreens Maximum Strength Jock Itch Antifungal, Meijer Maximum Strength Anthletes foot Antifungal, Meijer Maximum Strength Athletes Foot Antifungal, LUCKY SUPER SOFT ANTIFUNGAL For Athletes Foot, Meijer Maximum Strength Jock Itch Relief Antifungal, Phytozine ringworm treatment maximum strength, Terramed Just Think Comfort Armor Antifungal Medicated, TOENAIL FUNGUS TREATMENT MAXIMUM STRENGTH Liquid
- Cat. No.
- P-T155-001
- CAS
- 2398-96-1
- Alternative CAS
- 94256-64-1 (alternative CAS, same compound)
- Formula
- C19H17NOS
- Molecular weight
- 307.41 g/mol
- Category
- Active ingredient (API)
A topical antifungal of the thiocarbamate class, discovered in Japan in 1962 by chemist Teruhisa Noguchi and used against athlete's foot, ringworm and other skin fungal infections; in most countries it is sold over the counter.
Did you know?It is not an azole: like terbinafine it appears to block squalene epoxidase, an enzyme fungi need to make the ergosterol of their membranes, and it is especially useful against ringworm caught from pets.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Tolnaftate CRSEP T1707000
- Tolnaftate for system suitability CRSEP Y0001123
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Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.