Family · Pharmaceutical analytical standards
Yohimbine
An indole alkaloid extracted from the bark of the yohimbe, a tree of western and central Africa, first isolated in 1896 by Adolph Spiegel. It blocks alpha-2 adrenergic receptors and in veterinary medicine is used to reverse xylazine sedation in dogs and deer. This family brings together the active ingredient, pharmacopoeial impurities, labelled standards and other impurities.
Did you know?Its chemical structure was only worked out in 1943 by Bernhard Witkop, almost half a century after its isolation; the first total synthesis, in 23 steps, came in 1958 from Eugene van Tamelen.
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EDQM standards 2
The official European Pharmacopoeia standards for this family.
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Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
