Active ingredientDapsoneCat. No. P-D018-001CAS 80-08-0
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Impurity or related compound · Dapsone family
Pharmaceutical analytical standard4-(4-Nitrophenyl)sulfinylaniline
Synonyms: Dapsone Impurity 14, Dapsone Impurity 9, NSC 5533
- Cat. No.
- P-D018-021
- CAS
- 5461-23-4
- Alternative CAS
- N/A
- Formula
- C12H10N2O3S
- Molecular weight
- 262.28 g/mol
- Category
- Impurity or related compound
Family: Dapsone
A sulfone antibacterial used against leprosy since 1945; together with a gluten-free diet it is also used for dermatitis herpetiformis, and as a second-line option against Pneumocystis pneumonia.
Did you know?It was synthesised in 1908 by chemists Fromm and Wittmann as a simple chemical compound and studied as an antibiotic only in 1937; it still has an industrial use too, as a curing agent for epoxy resins.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Dapsone family
Active ingredientDapsoneCat. No. P-D018-001CAS 80-08-0
Pharmacopoeial impurityDapsone EP Impurity ACat. No. P-D018-002CAS 25963-47-7
Pharmacopoeial impurityDapsone EP Impurity BCat. No. P-D018-003CAS 7019-01-4
Pharmacopoeial impurityDapsone EP Impurity CCat. No. P-D018-004CAS 54616-64-7
Pharmacopoeial impurityDapsone EP Impurity C HCl SaltCat. No. P-D018-005
Pharmacopoeial impurityDapsone EP Impurity DCat. No. P-D018-006CAS 27147-69-9
Pharmacopoeial impurityDapsone EP Impurity ECat. No. P-D018-007CAS 7146-68-1
Pharmacopoeial impurityDapsone EP Impurity FCat. No. P-D018-008CAS 80-00-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.