Active ingredientHydrocortisoneCat. No. P-H040-001CAS 50-23-7
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Impurity or related compound · Hydrocortisone family
Pharmaceutical analytical standard5-beta-Dihydrocortisone
Synonyms: 4,5beta-Dihydrocortisone, Dihydrocortisone, (5beta)-, Pregnane-3,11,20-trione, 17,21-dihydroxy-, (5beta)-
- Cat. No.
- P-H040-054
- CAS
- 68-54-2
- Alternative CAS
- N/A
- Formula
- C21H30O5
- Molecular weight
- 362.47 g/mol
- Category
- Impurity or related compound
Family: Hydrocortisone
It is cortisol, the stress hormone made by the adrenal glands, isolated in the 1930s. It is used to replace the hormone when it is missing and to switch off inflammation and allergies.
Did you know?Research on adrenal hormones won Kendall, Hench and Reichstein the 1950 Nobel Prize in Medicine: the first patient treated with cortisone, in 1948, had severe rheumatoid arthritis and was walking again within days.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Hydrocortisone family
Active ingredientHydrocortisoneCat. No. P-H040-001CAS 50-23-7
ImpurityHydrocortisone 17-phosphateCat. No. P-H040-002CAS 220489-76-9
Active ingredientHydrocortisone AcetateCat. No. P-H040-003CAS 50-03-3
Active ingredientHydrocortisone Hydrogen SuccinateCat. No. P-H040-004CAS 2203-97-6
Active ingredientHydrocortisone Sodium PhosphateCat. No. P-H040-005CAS 6000-74-4
Active ingredientHydrocortisone Sodium SuccinateCat. No. P-H040-006CAS 125-04-2
ImpurityHydrocortisone-17-SuccinateCat. No. P-H040-007CAS 220489-73-6
Pharmacopoeial impurityHydrocortisone Acetate EP Impurity GCat. No. P-H040-008CAS 81968-66-3Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.