Active ingredientAlvimopanCat. No. P-A102-001CAS 156053-89-3
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Metabolite · Alvimopan family
Pharmaceutical analytical standardAlvimopan Metabolite 1 Hydrochloride
Synonyms: ADL 08-0011 HCl, ADL 08-0011 (hydrochloride)
- Cat. No.
- P-A102-006
- CAS
- 170098-43-8
- Alternative CAS
- 156130-41-5 (free base)
- 170098-35-8 (hydrate)
- Formula
- C23H29NO3·HCl
- Molecular weight
- 403.95 g/mol
- Category
- Metabolite
Family: Alvimopan
A peripherally acting mu-opioid receptor antagonist, approved in the United States in 2008 to speed up the recovery of bowel function after surgery to remove part of the intestine.
Did you know?It stays almost entirely in the gut: less than 7% reaches the blood and the little that gets to the brain is pumped back out, so it curbs the effect of opioids on the bowel without reducing pain relief.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Alvimopan family
Active ingredientAlvimopanCat. No. P-A102-001CAS 156053-89-3
Active ingredientAlvimopan DihydrateCat. No. P-A102-002CAS 170098-38-1
MetaboliteAlvimopan Phenolic SulfateCat. No. P-A102-003
MetaboliteAlvimopan Acyl Glucuronide (mixture of isomers)Cat. No. P-A102-004CAS 1260616-95-2
MetaboliteAlvimopan MetaboliteCat. No. P-A102-005CAS 156130-41-5
MetaboliteAlvimopan Phenolic Glucuronide (mixture of isomers)Cat. No. P-A102-007
Isotopically labelledAlvimopan Metabolite 1-d5Cat. No. P-A102-008CAS 2124272-23-5
Isotopically labelledAlvimopan-d5 (Mixture of Diastereomers)Cat. No. P-A102-009CAS 1217616-62-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.