Active ingredientAmilorideCat. No. P-A119-001CAS 2609-46-3
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Active ingredient · Amiloride family
Pharmaceutical analytical standardAmiloride Hydrochloride Dihydrate
Synonyms: Modamide, Amilorid hydrochlorid-2-wasser, AMIPRAMIDINE, Amilamont, Amoride, Berkamil, Pyrazinecarboxamide, N-amidino-3,5-diamino-6-chloro-, monohydrochloride, Amipramizide, N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide monohydrochloride dihydrate, Nirulid, N-Amidino-3,5-diamino-6-chloropyrazinamide hydrochloride dihydrate, N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride dihydrate, Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride dihydrate, Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-,monohydrochloride, Midamor, Guanamprazine dihydrate, Amipramidin hydrochloride dihydrate, Amiloride Hydrochloride, Amiloride hydrochloride anhydrous, Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride, N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide monohydrochloride, N-Amido-3,5-diamino-6-chloropyrazine carboxamide hydrochloride dihydrate, N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride
- Cat. No.
- P-A119-002
- CAS
- 17440-83-4
- Alternative CAS
- 2609-46-3 (free base)
- 137053-86-2 (free base)
- 2016-88-8 (anhydrous form)
- Formula
- C6H8ClN7O·HCl·2H2O
- Molecular weight
- 302.12 g/mol
- Category
- Active ingredient (API)
Family: Amiloride
A potassium-sparing diuretic developed in the late 1960s: it blocks the epithelial sodium channel (ENaC) in the kidney and is used, often with other diuretics, for high blood pressure and oedema.
Did you know?It is the treatment of choice for Liddle syndrome, a rare inherited form of high blood pressure caused by overactive ENaC channels, which the drug blocks directly.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Amiloride HydrochlorideBP 008
- Amiloride for peak identification CRSEP Y0001902
- Amiloride hydrochloride CRSEP A0370000
More products in the Amiloride family
Active ingredientAmilorideCat. No. P-A119-001CAS 2609-46-3
Pharmacopoeial impurityAmiloride EP Impurity ACat. No. P-A119-004CAS 1458-01-1
Pharmacopoeial impurityAmiloride EP Impurity BCat. No. P-A119-005CAS 4878-36-8
Pharmacopoeial impurityAmiloride EP Impurity CCat. No. P-A119-006CAS 76599-74-1
Pharmacopoeial impurityAmiloride EP Impurity C HClCat. No. P-A119-007CAS 1207-29-0
Isotopically labelledAmiloride-15N3Cat. No. P-A119-008CAS 1217169-93-1
Isotopically labelledAmiloride-15N3 HydrochlorideCat. No. P-A119-009CAS 1216796-18-7
Impurity3-Aminopyrazine-2-carboxylic AcidCat. No. P-A119-010CAS 5424-01-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.